Virus-induced increases in bronchiolar mast cells in Brown Norway rats are associated with both local mast cell proliferation and increases in blood mast cell …

SD Sorden, WL Castleman - … ; a journal of technical methods and …, 1995 - europepmc.org
SD Sorden, WL Castleman
Laboratory investigation; a journal of technical methods and pathology, 1995europepmc.org
Background Parainfluenza type 1 (Sendai) virus-induced bronchiolitis during early life in rats
induces increases in bronchiolar mast cells that persist for months after infection and are
associated with airway obstruction and airway hyperresponsiveness. Brown Norway (BN)
rats are highly susceptible, and Fischer 344 (F344) rats are relatively resistant to, Sendai
virus-induced increases in airway responsiveness and mast cell density.
Background
Parainfluenza type 1 (Sendai) virus-induced bronchiolitis during early life in rats induces increases in bronchiolar mast cells that persist for months after infection and are associated with airway obstruction and airway hyperresponsiveness. Brown Norway (BN) rats are highly susceptible, and Fischer 344 (F344) rats are relatively resistant to, Sendai virus-induced increases in airway responsiveness and mast cell density.
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