Microglia are the primary responders to central nervous system insults; however, much
remains unknown about their role in regulating neuroinflammation. Microglia are
mesodermal cells that function similarly to macrophages in surveying inflammatory stress.
The classical (M1-type) and alternative (M2-type) activations of macrophages have also
been extended to microglia in an effort to better understand the underlying interplay these
phenotypes have in neuroinflammatory conditions such as Parkinson's, Alzheimer's, and …