Schistosoma mansoni: SmE78, a nuclear receptor orthologue of Drosophila ecdysone-induced protein 78
W Wu, EY Tak, PT LoVerde - Experimental parasitology, 2008 - Elsevier
Drosophila ecdysone-induced protein 78 (E78) belongs to the nuclear receptor (NR)
superfamily, it plays a role directly related to ecdysone signaling. We isolated a cDNA of
Drosophila E78 orthologue from the Platyhelminth Schistosoma mansoni (SmE78). It is the
first E78 orthologue known outside of the molting animals—the Ecdysozoa. The SmE78
cDNA is 3471 base pairs long and contains an entire open reading frame (ORF) encoding a
1087 amino acid protein. Phylogenetic analysis of the ligand-binding domain (LBD) …
superfamily, it plays a role directly related to ecdysone signaling. We isolated a cDNA of
Drosophila E78 orthologue from the Platyhelminth Schistosoma mansoni (SmE78). It is the
first E78 orthologue known outside of the molting animals—the Ecdysozoa. The SmE78
cDNA is 3471 base pairs long and contains an entire open reading frame (ORF) encoding a
1087 amino acid protein. Phylogenetic analysis of the ligand-binding domain (LBD) …