Nonalcoholic fatty liver disease

P Angulo - New England Journal of Medicine, 2002 - Mass Medical Soc
P Angulo
New England Journal of Medicine, 2002Mass Medical Soc
Alcohol abuse is the most common cause of fatty liver disease, but it is now apparent that fat
deposition in the liver, and its consequences, may occur without alcohol abuse. The
principal risk factors are obesity, non-insulin-dependent diabetes mellitus, and
hyperlipidemia. The disorder has a wide clinical spectrum, ranging from asymptomatic
steatosis to steatohepatitis, fibrosis, and cirrhosis. This article provides a broad overview of
this increasingly recognized liver disease.
Alcohol abuse is the most common cause of fatty liver disease, but it is now apparent that fat deposition in the liver, and its consequences, may occur without alcohol abuse. The principal risk factors are obesity, non-insulin-dependent diabetes mellitus, and hyperlipidemia. The disorder has a wide clinical spectrum, ranging from asymptomatic steatosis to steatohepatitis, fibrosis, and cirrhosis. This article provides a broad overview of this increasingly recognized liver disease.
The New England Journal Of Medicine