The respective life histories of human subjects and mice are well defined and describe a
unique story of evolutionary conservation extending from sequence identity within the
genome to the underpinnings of biochemical, cellular, and physiologic pathways. As a
consequence, the hematopoietic lineages of both species are invariantly maintained, each
with identifiable eosinophils. This canonical presence nonetheless does not preclude
disparities between human and mouse eosinophils, their effector functions, or both. Indeed …