Objective To review and highlight the unappreciated roles of eosinophils suggested by
recent studies. Data Sources The literature, unpublished observations, and insights by the
authors. Study Selections Basic studies of mouse models and patient-based clinical studies
of disease. Results Eosinophils are often thought of as destructive end-stage effector cells
primarily linked to parasite host defense and dysregulated immune responses associated
with allergic diseases, such as asthma. However, recent studies (ie, research focused on …