mTOR and the control of whole body metabolism

P Polak, MN Hall - Current opinion in cell biology, 2009 - Elsevier
Current opinion in cell biology, 2009Elsevier
Mammalian Target of Rapamycin (mTOR) is a highly conserved protein kinase that functions
as part of two distinct multiprotein complexes to regulate growth and metabolism. This
review describes the most important recent advances in the mTOR signaling field. In
addition, we provide an overview on the functions of mTOR in different organs, with a special
focus on the role of mTOR in whole body energy metabolism.
Mammalian Target of Rapamycin (mTOR) is a highly conserved protein kinase that functions as part of two distinct multiprotein complexes to regulate growth and metabolism. This review describes the most important recent advances in the mTOR signaling field. In addition, we provide an overview on the functions of mTOR in different organs, with a special focus on the role of mTOR in whole body energy metabolism.
Elsevier