[HTML][HTML] Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter
ECH Friesema, S Ganguly, A Abdalla, JEM Fox… - Journal of Biological …, 2003 - ASBMB
Transport of thyroid hormone across the cell membrane is required for its action and
metabolism. Recently, a T-type amino acid transporter was cloned which transports aromatic
amino acids but not iodothyronines. This transporter belongs to the monocarboxylate
transporter (MCT) family and is most homologous with MCT8 (SLC16A2). Therefore, we
cloned rat MCT8 and tested it for thyroid hormone transport in Xenopus laevis oocytes.
Oocytes were injected with rat MCT8 cRNA, and after 3 days immunofluorescence …
metabolism. Recently, a T-type amino acid transporter was cloned which transports aromatic
amino acids but not iodothyronines. This transporter belongs to the monocarboxylate
transporter (MCT) family and is most homologous with MCT8 (SLC16A2). Therefore, we
cloned rat MCT8 and tested it for thyroid hormone transport in Xenopus laevis oocytes.
Oocytes were injected with rat MCT8 cRNA, and after 3 days immunofluorescence …
