Epicutaneous allergen-specific immunotherapy ameliorates grass pollen–induced rhinoconjunctivitis: A double-blind, placebo-controlled dose escalation study
G Senti, S von Moos, F Tay, N Graf… - Journal of allergy and …, 2012 - Elsevier
BACKGROUND: Epicutaneous allergen administration using a patch may be an alternative
to subcutaneous or sublingual immunotherapy. OBJECTIVE: To optimize treatment dose
and to demonstrate the efficacy and safety of epicutaneous immunotherapy. METHODS:
This monocentric, placebo-controlled, double-blind trial included 132 patients with grass
pollen–induced rhinoconjunctivitis. In February 2008, patients were randomly allocated to
receive placebo or 3 different doses of allergen. Before and during the pollen season 2008 …
to subcutaneous or sublingual immunotherapy. OBJECTIVE: To optimize treatment dose
and to demonstrate the efficacy and safety of epicutaneous immunotherapy. METHODS:
This monocentric, placebo-controlled, double-blind trial included 132 patients with grass
pollen–induced rhinoconjunctivitis. In February 2008, patients were randomly allocated to
receive placebo or 3 different doses of allergen. Before and during the pollen season 2008 …