Long-term follow-up of oral immunotherapy for cow's milk allergy
CA Keet, S Seopaul, S Knorr, S Narisety… - Journal of Allergy and …, 2013 - jacionline.org
Both previously published studies enrolled children with CM allergy at Johns Hopkins and
Duke Universities after a doubleblind, placebo-controlled oral food challenge (OFC). 4-6
The first study was a double-blind, placebo-controlled trial in 20 children. 4 Dose escalation
to 0.5 g of CM protein lasted approximately 8 weeks, followed by 3-month maintenance. All
placebo-treated children were offered active OIT after the final OFC. The second study was
an open-label randomized trial of OIT versus sublingual immunotherapy in 30 children. 6 …
Duke Universities after a doubleblind, placebo-controlled oral food challenge (OFC). 4-6
The first study was a double-blind, placebo-controlled trial in 20 children. 4 Dose escalation
to 0.5 g of CM protein lasted approximately 8 weeks, followed by 3-month maintenance. All
placebo-treated children were offered active OIT after the final OFC. The second study was
an open-label randomized trial of OIT versus sublingual immunotherapy in 30 children. 6 …