Oral immunotherapy for milk allergy

JP Yeung, LA Kloda, J McDevitt… - Cochrane database …, 2012 - cochranelibrary.com
JP Yeung, LA Kloda, J McDevitt, M Ben‐Shoshan, R Alizadehfar
Cochrane database of systematic reviews, 2012cochranelibrary.com
Background The mainstay of treatment of IgE‐mediated cow milk allergy (IMCMA) is an
avoidance diet, which is especially difficult with a ubiquitous food like milk. Milk oral
immunotherapy (MOIT) may be an alternative treatment, through desensitization or induction
of tolerance. Objectives We aim to assess the clinical efficacy and safety of MOIT in children
and adults with IMCMA as compared to a placebo treatment or avoidance strategy.
Background
The mainstay of treatment of IgE‐mediated cow milk allergy (IMCMA) is an avoidance diet, which is especially difficult with a ubiquitous food like milk. Milk oral immunotherapy (MOIT) may be an alternative treatment, through desensitization or induction of tolerance.
Objectives
We aim to assess the clinical efficacy and safety of MOIT in children and adults with IMCMA as compared to a placebo treatment or avoidance strategy.
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