Oral immunotherapy for cow's milk allergy with a weekly up-dosing regimen: a randomized single-blind controlled study

GB Pajno, L Caminiti, P Ruggeri, R De Luca… - Annals of Allergy …, 2010 - Elsevier
BACKGROUND: Cow's milk allergy (CMA) in children is a important problem in medical
practice. Oral desensitization has been proposed as a therapeutic approach, but current
protocols are time-consuming and impractical. OBJECTIVES: To establish a patient-friendly
desensitization regimen with weekly up-dosing and to evaluate it in a randomized controlled
trial. METHODS: Thirty children with IgE-mediated CMA confirmed by double-blind placebo-
controlled food challenge were equally randomized to desensitization with CM or soy milk …