Oral peanut immunotherapy in children with peanut anaphylaxis

K Blumchen, H Ulbricht, U Staden… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: The only treatment option for peanut allergy is strict avoidance.
OBJECTIVE: To investigate efficacy and safety of oral immunotherapy (OIT) in peanut
allergy. METHODS: Twenty-three children (age, 3.2-14.3 years) with IgE-mediated peanut
allergy confirmed by positive double-blind, placebo-controlled food challenge (DBPCFC)
received OIT following a rush protocol with roasted peanut for 7 days. If a protective dose of
at least 0.5 g peanut was not achieved, patients continued with a long-term buildup protocol …