Safety of a peanut oral immunotherapy protocol in children with peanut allergy

AM Hofmann, AM Scurlock, SM Jones… - Journal of allergy and …, 2009 - Elsevier
BACKGROUND: Oral immunotherapy (OIT) offers a promising therapeutic option for peanut
allergy. Given that during OIT an allergic patient ingests an allergen that could potentially
cause a serious reaction, the safety of OIT is of particular concern. OBJECTIVE: The purpose
of this study was to examine safety during the initial escalation day, buildup phase, and
home dosing phase in subjects enrolled in a peanut OIT study. METHODS: Skin, upper
respiratory tract, chest, and abdominal symptoms were recorded with initial escalation day …