Milk-induced urticaria is associated with the expansion of T cells expressing cutaneous lymphocyte antigen

K Beyer, R Castro, C Feidel, HA Sampson - Journal of allergy and clinical …, 2002 - Elsevier
Background: Two forms of IgE-mediated skin reactions, atopic dermatitis (AD) and urticaria,
have been associated with milk allergy. The reason for these distinct reactions is poorly
understood. T cells expressing cutaneous lymphocyte antigen (CLA), a unique skin-homing
receptor, are known to play an important role in AD. In contrast, the role of lymphocytes in
patients with milk-induced urticaria is unclear. Objective: The expression of the skin-specific
homing receptor CLA after in vitro milk protein—specific stimulation was investigated to …