[HTML][HTML] Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow …
M Andreani, M Testi, J Gaziev, R Condello… - …, 2011 - ncbi.nlm.nih.gov
haematologica, 2011•ncbi.nlm.nih.gov
Background Persistent mixed chimerism represents a state in which recipient and donor
cells stably co-exist after hematopoietic stem cell transplantation. However, since in most of
the studies reported in literature the engraftment state was observed in the nucleated cells,
in this study we determined the donor origin of the mature erythrocytes of patients with
persistent mixed chimerism after transplantation for hemoglobinopathies. Results were
compared with the engraftment state observed in singly picked out burst-forming unit …
cells stably co-exist after hematopoietic stem cell transplantation. However, since in most of
the studies reported in literature the engraftment state was observed in the nucleated cells,
in this study we determined the donor origin of the mature erythrocytes of patients with
persistent mixed chimerism after transplantation for hemoglobinopathies. Results were
compared with the engraftment state observed in singly picked out burst-forming unit …
Abstract
Background
Persistent mixed chimerism represents a state in which recipient and donor cells stably co-exist after hematopoietic stem cell transplantation. However, since in most of the studies reported in literature the engraftment state was observed in the nucleated cells, in this study we determined the donor origin of the mature erythrocytes of patients with persistent mixed chimerism after transplantation for hemoglobinopathies. Results were compared with the engraftment state observed in singly picked out burst-forming unit–erythroid colonies and in the nucleated cells collected from the peripheral blood and from the bone marrow.
ncbi.nlm.nih.gov
