Fc receptors

MS Powell, PM Hogarth - Multichain Immune Recognition Receptor …, 2008 - Springer
MS Powell, PM Hogarth
Multichain Immune Recognition Receptor Signaling: From Spatiotemporal …, 2008Springer
The aggregation of cell surface Fc receptors by immune complexes induces a number of
important antibody-dependent effector functions. It is becoming increasingly evident that the
organization of key immune proteins has a significant impact on the function of these
proteins. Comparatively little is known, however, about the nature of Fc receptor
spatiotemporal organization. This review outlines the current literature concerning human Fc
receptor spatial organization and physiological function.
Abstract
The aggregation of cell surface Fc receptors by immune complexes induces a number of important antibody-dependent effector functions. It is becoming increasingly evident that the organization of key immune proteins has a significant impact on the function of these proteins. Comparatively little is known, however, about the nature of Fc receptor spatiotemporal organization. This review outlines the current literature concerning human Fc receptor spatial organization and physiological function.
Springer