[HTML][HTML] Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth

H Chen, W Yong, S Ren, W Shen, Y He, KA Cox… - Journal of Biological …, 2006 - ASBMB
Postnatal cardiac hypertrophies have traditionally been classified into physiological or
pathological hypertrophies. Both of them are induced by hemodynamic load. Cardiac
postnatal hypertrophic growth is regarded as a part of the cardiac maturation process that is
independent of the cardiac working load. However, the functional significance of this
biological event has not been determined, mainly because of the difficulty in creating an
experimental condition for testing the growth potential of functioning heart in the absence of …