Iron is an essential cofactor for enzymes involved in numerous cellular processes, yet little is
known about the impact of iron deficiency on cellular metabolism or iron proteins. Previous
studies have focused on changes in transcript and proteins levels in iron-deficient cells, yet
these changes may not reflect changes in transport activity or flux through a metabolic
pathway. We analyzed the metabolomes and transcriptomes of yeast grown in iron-rich and
iron-poor media to determine which biosynthetic processes are altered when iron availability …