Karyotypic evolution in breast carcinomas with i (1)(q10) and der (1; 16)(q10; p10) as the primary chromosome abnormality
H Tsarouha, N Pandis, G Bardi, MR Teixeira… - Cancer genetics and …, 1999 - Elsevier
The pattern of clonal karyotypic evolution in breast carcinomas carrying an i (1q) or a der (1;
16)(q10; p10) as the primary chromosome abnormality was assessed in a series of 42
tumors, including 8 described here for the first time, with either or both (3 tumors) of them
defining cytogenetic features. Evidence of clonal evolution was seen in somewhat more than
half of all cases in both subgroups. The secondarily acquired aberrations appeared to be
nonrandom in distribution. This was especially so for structural rearrangements of 11q …
16)(q10; p10) as the primary chromosome abnormality was assessed in a series of 42
tumors, including 8 described here for the first time, with either or both (3 tumors) of them
defining cytogenetic features. Evidence of clonal evolution was seen in somewhat more than
half of all cases in both subgroups. The secondarily acquired aberrations appeared to be
nonrandom in distribution. This was especially so for structural rearrangements of 11q …