Transitioning to therapy in ischemic acute renal failure

BA Molitoris - Journal of the American society of nephrology, 2003 - journals.lww.com
Ischemic acute renal failure (ARF) remains an area of immense clinical importance and cost.
Outstanding advances in understanding the cellular and molecular aspects have occurred,
yet little progress has been made in the translation of these findings to the clinical arena. In
this issue of JASN, two important articles provide additional contributions to our
understanding of the cellular events that mediate injury and subsequent cell death in renal
tubule epithelial cells. Before discussing these articles individually, the context of their …