The IgE and IgG subclass antibody response to foods in babies during the first year of life and their relationship to feeding regimen and the development of food …

DM Kemeny, JF Price, V Richardson, D Richards… - Journal of allergy and …, 1991 - Elsevier
This follow-up study of 191 babies investigated the development of food allergy in an
unselected population and its relationship to total and antigen-specific IgE and IgG subclass
levels. Sensitization to egg, as indicated by a positive skin test or RAST, was found in 5% of
1-year-old babies, but none of the babies in this series fulfilled the clinical criteria for
immediate-type milk allergy. For both bovine casein (CAS) and egg albumin, the IgG
response was largely restricted to IgG1 in contrast to the predominant IgG4 response to …