The role of the macrophage in immune regulation

S Gordon - Research in immunology, 1998 - Elsevier
The macrophage plays an important role in both the innate and acquired (humoral and
cellular) immune responses. Their specialized derivatives, the dendritic cells (DCs), are
uniquely potent in induction of naive T and B lymphocytes, whereas macrophages influence
a range of immune responses by antigen recognition, capture, clearance and transport.
They recruit haemopoietic cells to local sites of inflammation and immunity and regulate their
activities. We have used various myeloid-restricted membrane antigens and receptors as …