Hypogammaglobulinemia and reduced numbers of B-cells in children with myelodysplastic syndrome
K Srivannaboon, ME Conley… - Journal of pediatric …, 2001 - journals.lww.com
Background Immunodeficiency in pediatric patients with myelodysplastic syndrome (MDS)
has not been described. We report the clinical course of three children with MDS,
hypogammaglobulinemia, and reduced numbers of B-cells and B-cell precursors.
Observations Three patients with recurrent infection who were younger than 1-year-old had
MDS of the refractory anemia (RA) subtype diagnosed. All had reduced numbers of
circulating B-cells and hypogammaglobulinemia. In two patients, cytogenetic studies …
has not been described. We report the clinical course of three children with MDS,
hypogammaglobulinemia, and reduced numbers of B-cells and B-cell precursors.
Observations Three patients with recurrent infection who were younger than 1-year-old had
MDS of the refractory anemia (RA) subtype diagnosed. All had reduced numbers of
circulating B-cells and hypogammaglobulinemia. In two patients, cytogenetic studies …
