Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial
HSL Chan, JA Correia, SM MacLeod - Pediatrics, 1987 - publications.aap.org
In a randomized, double-blind, crossover trial, nabilone was compared to prochlorperazine
for control of cancer chemotherapy-induced emesis in 30 children 3.5 to 17.8 years of age.
All subjects received two consecutive identical cycles of chemotherapy with the trial
antiemetics given in accordance to a body weight-based dosage schedule beginning eight
to 12 hours before treatment. The overall rate of improvement of retching and emesis was
70% during the nabilone and 30% during the prochlorperazine treatment cycles (P=. 003, χ2 …
for control of cancer chemotherapy-induced emesis in 30 children 3.5 to 17.8 years of age.
All subjects received two consecutive identical cycles of chemotherapy with the trial
antiemetics given in accordance to a body weight-based dosage schedule beginning eight
to 12 hours before treatment. The overall rate of improvement of retching and emesis was
70% during the nabilone and 30% during the prochlorperazine treatment cycles (P=. 003, χ2 …
