Δ9-Tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis

WD Lyman, JR Sonett, CF Brosnan, R Elkin… - Journal of …, 1989 - Elsevier
Since multiple sclerosis (MS) is believed to be an immune-mediated disease, it follows that
its therapies should be directed towards modulating the immune system. Current MS
treatments, which include the use of exogenous steroids that are immunosuppressive, do
not meet therapeutic objectives. Δ 9-Tetrahydrocannabinol (THC), an active component of
marijuana, has been shown to be immunosuppressive. To test THC's ability to suppress an
immune-mediated disease, experimental autoimmune encephalomyelitis (EAE), the …