[HTML][HTML] The murine cysteinyl leukotriene 2 (CysLT2) receptor: cDNA and genomic cloning, alternative splicing, and in vitro characterization
Y Hui, G Yang, H Galczenski, DJ Figueroa… - Journal of Biological …, 2001 - ASBMB
Two classes of cysteinyl leukotriene receptor, CysLT 1 and CysLT 2, have been identified
and pharmacologically characterized in human tissues. Although the CysLT 1 receptor
mediates the proinflammatory effects of leukotrienes in human asthma, the physiological
roles of CysLT 2 receptor are not defined, and a suitable mouse model would be useful in
delineating function. We report here the molecular cloning and characterization of the
mouse CysLT 2 receptor (mCysLT 2 R) from heart tissue. mCysLT 2 R cDNA encodes a …
and pharmacologically characterized in human tissues. Although the CysLT 1 receptor
mediates the proinflammatory effects of leukotrienes in human asthma, the physiological
roles of CysLT 2 receptor are not defined, and a suitable mouse model would be useful in
delineating function. We report here the molecular cloning and characterization of the
mouse CysLT 2 receptor (mCysLT 2 R) from heart tissue. mCysLT 2 R cDNA encodes a …
