Amniotic fluid–soluble vascular endothelial growth factor receptor-1 in preeclampsia

P Vuorela, S Helske, C Hornig, K Alitalo, H Weich… - Obstetrics & …, 2000 - Elsevier
Objective: To measure the levels of the soluble receptor for the potent angiogenic agent
vascular endothelial growth factor (VEGF) in amniotic fluid (AF) in healthy and complicated
pregnancies, and compare them with levels of erythropoietin, another factor upregulated by
hypoxia. Methods: We assessed amniotic fluid from the second (n= 35, gestational weeks 14–
19) and third (n= 29) trimesters of healthy women, and from the third trimesters of
preeclamptic (n= 22) and diabetic women with (n= 11) or without preeclampsia (n= 34) and …