Proliferation of neuronal precursor cells in the dentate gyrus is accelerated after transient forebrain ischemia in mice
Y Takagi, K Nozaki, J Takahashi, J Yodoi, M Ishikawa… - Brain research, 1999 - Elsevier
Y Takagi, K Nozaki, J Takahashi, J Yodoi, M Ishikawa, N Hashimoto
Brain research, 1999•ElsevierWe investigated the proliferation of neuronal progenitor cells by labeling dividing cells by
systemic application of the thymidine analog 5-bromodeoxyuridine (BrdU) during transient
forebrain ischemia in mice. At 3 (n= 6), 7 (n= 6), 10 (n= 6), and 17 days (n= 6) after
reperfusion, BrdU-labeled cells were detected in the dentate gyrus and paraventricle lesion.
After ischemia-reperfusion, BrdU-labeled cells in the dentate gyrus significantly increased in
number but not in the paraventricle lesion. These observations may help to clarify the …
systemic application of the thymidine analog 5-bromodeoxyuridine (BrdU) during transient
forebrain ischemia in mice. At 3 (n= 6), 7 (n= 6), 10 (n= 6), and 17 days (n= 6) after
reperfusion, BrdU-labeled cells were detected in the dentate gyrus and paraventricle lesion.
After ischemia-reperfusion, BrdU-labeled cells in the dentate gyrus significantly increased in
number but not in the paraventricle lesion. These observations may help to clarify the …
We investigated the proliferation of neuronal progenitor cells by labeling dividing cells by systemic application of the thymidine analog 5-bromodeoxyuridine (BrdU) during transient forebrain ischemia in mice. At 3 (n=6), 7 (n=6), 10 (n=6), and 17 days (n=6) after reperfusion, BrdU-labeled cells were detected in the dentate gyrus and paraventricle lesion. After ischemia-reperfusion, BrdU-labeled cells in the dentate gyrus significantly increased in number but not in the paraventricle lesion. These observations may help to clarify the mechanism of functional recovery after stroke.
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