The ecology of genetically diverse infections

AF Read, LH Taylor - Science, 2001 - science.org
AF Read, LH Taylor
Science, 2001science.org
Microparasite infections often consist of genetically distinct clonal lineages. Ecological
interactions between these lineages within hosts can influence disease severity,
epidemiology, and evolution. Many medical and veterinary interventions have an impact on
genetic diversity within infections, but there is little understanding of the long-term
consequences of such interventions for public and animal health. Indeed, much of the theory
in this area is based on assumptions contradicted by the available data.
Microparasite infections often consist of genetically distinct clonal lineages. Ecological interactions between these lineages within hosts can influence disease severity, epidemiology, and evolution. Many medical and veterinary interventions have an impact on genetic diversity within infections, but there is little understanding of the long-term consequences of such interventions for public and animal health. Indeed, much of the theory in this area is based on assumptions contradicted by the available data.
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