[CITATION][C] [10] Iodination of chemokines for use in receptor binding analysis
GL Bennett, R Horuk - Methods in enzymology, 1997 - Elsevier
An understanding of the interaction between cell surface receptors and extraceUular factors
such as polypeptide hormones is critical to gain insight into the mechanisms by which these
molecules can regulate intracellular processes. The rapid advances made in understanding
cellular signaling can in part be attributed to the development of reliable receptor binding
assays. Crucial to this rapid progress in receptor research has been the ability to effectively
radiolabel receptor ligands with full retention of their biological activity. Indeed, successful …
such as polypeptide hormones is critical to gain insight into the mechanisms by which these
molecules can regulate intracellular processes. The rapid advances made in understanding
cellular signaling can in part be attributed to the development of reliable receptor binding
assays. Crucial to this rapid progress in receptor research has been the ability to effectively
radiolabel receptor ligands with full retention of their biological activity. Indeed, successful …