6 Seeking Muscle Stem Cells

JB Miller, L Schaefer, JA Dominov - Current topics in developmental …, 1998 - Elsevier
Publisher Summary This chapter discusses the experiments that have shaped ones ideas of
cellular and molecular mechanisms in myogenesis. It discusses the experiments regarding
the existence and nature of muscle stem cells. An important feature of myogenesis is the
formation of specialized types of fast and slow muscle fibers that are arrayed in distinctive
patterns in different muscles. Skeletal muscle development requires the formation of
myoblasts that can fuse with each other to form multinucleate myofibers. Distinct primary and …